Reflections on the Nature and Future of Systematic Review in Healthcare.  by Barry Robson PhD DSc (Rough Draft, Version 1.0, Feb 22 2015) 1. Systematic Review  A systematic review (SR) is “a high-level overview of primary research on a particular research question that tries to identify, select, synthesize and appraise all high quality research evidence relevant to that question in order to answer it” [1]. The systematic review is an approach to decision making to healthcare that is promoted by the Cochrane Collaboration [1]. The Cochrane Collaboration prepares, maintains and promotes systematic reviews to inform healthcare decisions as “Cochrane Reviews”. The approach is based upon the views expressed by Archie Cochrane [2] as to what strategy should be applied in healthcare in order to best benefit patients, and not least to avoid harming them. The general approach is consistent with that David Sackett [3] and Muir Gray [4] who framed, implemented, and refined Cochrane’s proposed methods as “Evidence Based Medicine”….

A Universal Exchange Language Solution Driving Semantic Interoperability and a BlockChain Approach to Healthcare and Biomedicine. Barry Robson and Srinidhi Boray; Ingine Inc. (www.ingine.com) Delaware   BioIngine.com’s Revolutionary Technology based on Q-UEL (Quantum Universal Exchange Language) and its derivative Hyperbolic Dirac Net (an advancement to Bayesian learning); designed in heaven for achieving Blockchain in Healthcare Interoperability. Particularly Following Features Designed to drive national and global standards for interoperability Designed to support digital certificates Patient data encryption (de-identification and identification) Patient records disaggregation (transaction chunks) and aggregation Patient data existing as meta-statements (smaller chunks of blockchain Multi-level encryption to support multi-tier consent management Workflow integration across interoperability Secured backtrack Synopsis. The essential features of the blockchain approach to healthcare and biomedical (including pharmaceutical) research has been researched by the authors and collaborators for many years, using a novel Universal Exchange Language, a protocol for managing data, information, and knowledge that maps to blockchain. Several preferable modes of use have emerged. It is a modular toolkit designed…

BARRY ROBSON Ingine Inc | Bioingine.com Director of Research and Professor of Biostatistics, Epidemiology, and Evidence Based Medicine, St. Matthew’s University School of Medicine and Chief Scientific Offi cer, The Dirac Foundation O.K. BAEK Senior Enterprise Solution Architect, Medical Informatics, Clinical Genomics, eScience and Emerging Industry Solutions

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